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Thioredoxin has also been proven to bind to ASK1 to inhibit its activity as a kinase [32]. This inhibition is attenuated by ROS that can lead to dimerization of thioredoxin [33]. Thioredoxin regulation from the glucocorticoid receptor by way of Affiliation with the DNA binding area has also been documented [34] which also is influenced by ROS. Far … Read More


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